منابع مشابه
Prompt cytomolecular identification of chromosome aberration in irradiated blood cells
Background: understanding the genomic alteration induced by ionizing radiation still remains to be a methodological challenge in genetic field. The energy released from this type of radiation can potentially causes structural and numerical alterations in lymphocytes, which in turn converts them into abnormal tumor cells. Chromosomal abnormalities associated with specific type of hematological m...
متن کاملRare chromosome structural aberration characterizing oncology malignancy.
UNLABELLED Ring chromosome aberration are rare abnormality potentially involving any chromosome in patients diagnosing in Oncology. The present review and case study has focused on the ring chromosome associated with oncology malignancies. MATERIAL AND METHODS An electronic peer review article search was performed systematically to obtain relevant literature with the CINAHL, Google scholar, a...
متن کاملIn vivo chromosome aberration test for hydroxyapetite in mice.
This study evaluates the cytotoxic and mutagenic effect of synthetic hydroxyapatite granules (source: School of Material and Mineral Resources Engineering, Universiti Sains Malaysia) in the bone marrow cells of mice. Mice are exposed to synthetic hydroxyapatite granules, the bone marrow cells are collected and observed for chromosome aberrations. No chromosome aberrations were noticed in the an...
متن کاملB. 10. Mutagenicity – in Vitro Mammalian Chromosome Aberration Test
The purpose of the in vitro chromosomal aberration test is to identify agents that cause structural chromosome aberrations in cultured mammalian cells (1)(2)(3). Structural aberrations may be of two types, chromosome or chromatid. With the majority of chemical mutagens, induced aberrations are of the chromatid type, but chromosome-type aberrations also occur. An increase in polyploidy may indic...
متن کاملPharmaceutical effluent induced chromosome aberration in rat bone marrow cells
This paper presents the genotoxic effect of effluent from a pharmaceutical plant in Ota, Ogun state, Nigeria using the rat bone-marrow metaphase chromosome assay. The effluent was examined for some standard physical and chemical properties. Rats were intraperitoneally exposed to 1%, 5%, 10%, 25% and 50% (v/v, effluent/distilled water) concentrations of the effluent for 48 hr. Distilled water an...
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ژورنال
عنوان ژورنال: Medical Journal of Indonesia
سال: 1993
ISSN: 2252-8083,0853-1773
DOI: 10.13181/mji.v2i1.3588